Milwaukee Brewers at Cincinnati Reds odds, picks and betting tips

The Milwaukee Brewers (87-70) play their second game of a three-game set against the Cincinnati Reds (73-84) Wednesday at Great American Ball Park. The Brewers took the series opener 4-2.

Brewers at Reds: Projected starting pitchers

RHP Jordan Lyles vs. RHP Tyler Mahle.

Lyles enters Wednesday with a 2.35 ERA through 10 starts with the Brewers. The team has gone 9-1 over those 10 starts. He owns an overall ERA of 3.94 in the second half including his few remaining starts from what was a disastrous tenure with the Pittsburgh Pirates. He has a 4.43 ERA as the road starter with either team. Last outing: Lyles gave up just one solo homer over 4 2/3 innings while striking out nine with three walks against the San Diego Padres.

Mahle continues auditioning for a rotation spot in 2020. He owns a 6.37 second-half ERA, mostly due to a poor stretch in July. His strikeout rate has dropped from 9.62 batters per nine innings in the first half to 7.28 in the second, but his walk and home run rates have also dropped considerably. Last outing: Mahle gave up two walks, one hit and one earned run over a six-inning quality start against the Chicago Cubs at Wrigley Field.

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Brewers at Reds: By the numbers

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  • The Brewers are up 9-8 in the head-to-head season series, having won each of the last two following a streak of five straight losses to the Reds.
  • The series is 7-10 against the over/under.
  • Milwaukee is the only team in baseball with a neutral run differential. Cincinnati is minus-four on the season.
  • The Brewers have won five straight games, all without MVP candidate OF Christian Yelich.
  • The Reds went just 2-7-1 against the over/under across their last 10 games. The Brewers went 3-7.
  • Milwaukee ranks 13th in baseball with a .764 team OPS against right-handed pitching. Cincinnati ranks 23rd with a .733 team rate.
  • Brewers at Reds: Key injuries

    Reds SS Freddy Galvis (knee) remains day-to-day, but hasn’t played since Sept. 14.

    Brewers at Reds: Odds, picks and betting tips

    Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 12:30 p.M. ET.

    Moneyline: The Brewers are the easy choice and the -150 odds aren’t too low. Go ahead with the moneyline, with a $10 wager returning a profit of $6.68.

    Run line: The better bet is the +105 odds for the Brewers to cover the line of -1.5 and win by two or more runs, as they did Tuesday.

    Over/under: Get the UNDER (9.5, -129) with Lyles limiting the Reds’ run output and Mahle coming off one of his strongest outings of the season.

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    Esten’s September record: 62-46.

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